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Latest tagged entries for 'ANTIDEPRESSANTS'


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Depression relapse more likely with continuous antidepressant treatment

Thursday, 17 January 2008 8:24 A GMT+01
Maintenance antidepressant medication is the most commonly used preventive strategy for depression, a highly recurrent disease.

SSRI antidepressant withdrawal symptoms may persist for months

Thursday, 17 January 2008 8:07 A GMT+01
When withdrawal symptoms ensue after discontinuation of a Selective Serotonin Re-Uptake Inhibitor antidepressant such as paroxetine (Paxil®), it is generally assumed they will last for a few weeks and then they will subside.

Selective reporting of antidepressant trials exaggerated the drugs' effectiveness

Thursday, 17 January 2008 12:05 A GMT+01
Selective publication in reporting results of antidepressant trials exaggerates the effectiveness of the drugs, according to a study in the New England Journal of Medicine.

Review of adverse effect profile, safety, and dosing of antidepressants

Tuesday, 15 January 2008 7:29 A GMT+01
In 2002, 8.5% of the US population purchased at least one prescription antidepressant. Given this relatively high rate of antidepressant use, best practices should be followed in choosing the correct medication and dosing,

Abstract: Use of benzodiazepines and SSRIs in middle-aged and older adults with anxiety disorders

Tuesday, 15 January 2008 7:20 A GMT+01
Purpose of this study was to examine the use of benzodiazepines and SSRIs/SNRIs over nine years of follow-up in middle-aged and older adults with diagnoses of panic disorder with or without agoraphobia, social phobia, or generalized anxiety disorder

Many physicians fail to heed call to monitor youth on antidepressants

Saturday, 22 December 2007 8:52 A GMT+01
Although the FDA's warning on antidepressant-associated suicide risks in young patients was followed by a dramatic change in prescribing patterns, clinicians have not been seeing patients more often after starting antidepressant prescriptions.

Research on children yielding valuable clinical information

Saturday, 22 December 2007 8:48 A GMT+01
A wealth of knowledge that's been generated from pragmatically designed, NIMH-funded clinical trials can help clinicians provide evidence-based care for children and adolescents.

Evidence doesn't support CYP450 gene testing to guide antidepressant selection

Friday, 21 December 2007 8:00 A GMT+01
Cytochrome P450 (CYP450) gene testing is currently not recommended to guide treatment with selective serotonin reuptake inhibitor (SSRI) drugs for patients with depression, concludes an expert panel report

Because I couldn't say it on the phone

Saturday, 15 December 2007 9:04 A GMT+01
I was recently at lunch with a few friends, one who had just been diagnosed with OCD that manifests itself in a need to straighten up everything around her, and I was all really? That's considered OCD?

Future antidepressants may be derived from human hormones

Wednesday, 12 December 2007 8:52 A GMT+01
Novel treatment strategies for major depression with broader treatment success or a more rapid onset of action would have immense impact on public health, a new study published in the current issue of Biological Psychiatry explains.

Gene variation may predict whether lithium augmentation will help antidepressant non responders

Friday, 7 December 2007 9:30 P GMT+01
As in most fields of medicine, psychiatry researchers are working to identify specific types of patients, through their individual genetic variations, that may better benefit from particular drugs or combinations of drugs than other patients.

Abstract: EEG alpha measures predict therapeutic response to a SSRI

Friday, 7 December 2007 7:51 A GMT+01
Background: There is growing evidence that individual differences among depressed patients on electrophysiologic (EEG), neuroimaging, and neurocognitive measures are predictive of therapeutic response to antidepressant drugs.

Antidepressants and suicidality - The debate continues

Wednesday, 5 December 2007 8:25 A GMT+01
To the Editor: Dr. Gibbons et al. pointed to recent trends in SSRI prescriptions and the rate of suicide in young people to suggest that the FDA warnings have contributed to the increase in the number of youth suicides from 2003 to 2004.

Exercise gene discover may lead to better, more natural antidepressants

Monday, 3 December 2007 7:15 A GMT+01
Boosting an exercise-related gene in the brain works as a powerful antidepressant in mice-a finding that could lead to a new anti-depressant drug target, according to a Yale School of Medicine report in Nature Medicine. "The VGF exercise-related gen

Examining the strengths and limitations of generic formulations of antidepressants

Sunday, 2 December 2007 7:51 A GMT+01
What factors most commonly influence clinician perceptions of different antidepressants?

Pilots safer on anti-depressants: study

Saturday, 1 December 2007 8:25 A GMT+01
Depressed pilots who take medication are no more likely to crash or make errors than others in the cockpit, but too few may be taking the drugs, an Australian study suggests.

Abstract: SET-C versus fluoxetine [Prozac®] in the treatment of childhood social phobia.

Monday, 26 November 2007 8:26 A GMT+01
Objective: To determine the efficacy of fluoxetine, pill placebo, and Social Effectiveness Therapy for Children (SET-C) for children and adolescents with social phobia.

Antidepressants increases lifespan in nematode model of aging

Friday, 23 November 2007 8:40 A GMT+01
A team of scientists led by Howard Hughes Medical Institute (HHMI) investigator Linda B. Buck has found that a drug used to treat depression can extend the lifespan of adult roundworms.

Gradual, 10% dose reductions dramatically reduce antidepressant discontinuation symptoms

Wednesday, 21 November 2007 8:06 A GMT+01
Ten percent weekly reductions in dose over 10 weeks can diminish discontinuation effects associated with many antidepressants of the selective serotonin reuptake inhibitor (SSRI) class.

Antidepressant use and suicide in young people

Tuesday, 20 November 2007 8:16 A GMT+01
Antidepressants should not be ruled out as treatment for young people with depression, especially since recent studies have shown no connection between these medications and suicide in younger patients,

Women, doctors differ on safety of depression drugs during pregnancy

Friday, 16 November 2007 7:56 A GMT+01
Only 10 percent of women think it is safe for women to take medication for depression while they are pregnant, compared to 68 percent of doctors, according to a new survey of women and physicians

Hyponatremia: A potentially serious side effect of antidepressant treatment in the elderly

Wednesday, 14 November 2007 8:51 A GMT+01
The wide margin of safety associated with the use of the SSRIs and SNRIs are a major reason these drugs have been so widely adopted.

Abstract: Fluoxetine [Prozac®] protects hippocampal plasticity during conditioned fear stress and prevents fear learning potentiation

Monday, 12 November 2007 7:49 A GMT+01
Contextual fear conditioning can produce both changes in hippocampal synaptic efficacy and potentiation of subsequent fear learning. Objectives In this study, we tested whether fluoxetine reverses these effects.

Discovery may bring tailored depression drugs a step closer

Friday, 9 November 2007 8:18 A GMT+01
When a treatment works for one person's depression, it does not always work for another person's. Findings from the University of Iowa may one day help doctors have a better idea of who will benefit from specific antidepressants,

Anesthetic points way to faster-acting antidepressants

Wednesday, 25 July 2007 1:37 A GMT+01
Experimental medication ketamine relieves depression in just hours - points to targets for new medications

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