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Latest tagged entries for 'SSRIS'


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SSRI antidepressant withdrawal symptoms may persist for months

Thursday, 17 January 2008 8:07 A GMT+01
When withdrawal symptoms ensue after discontinuation of a Selective Serotonin Re-Uptake Inhibitor antidepressant such as paroxetine (Paxil®), it is generally assumed they will last for a few weeks and then they will subside.

Abstract: Use of benzodiazepines and SSRIs in middle-aged and older adults with anxiety disorders

Tuesday, 15 January 2008 7:20 A GMT+01
Purpose of this study was to examine the use of benzodiazepines and SSRIs/SNRIs over nine years of follow-up in middle-aged and older adults with diagnoses of panic disorder with or without agoraphobia, social phobia, or generalized anxiety disorder

Many physicians fail to heed call to monitor youth on antidepressants

Saturday, 22 December 2007 8:52 A GMT+01
Although the FDA's warning on antidepressant-associated suicide risks in young patients was followed by a dramatic change in prescribing patterns, clinicians have not been seeing patients more often after starting antidepressant prescriptions.

Evidence doesn't support CYP450 gene testing to guide antidepressant selection

Friday, 21 December 2007 8:00 A GMT+01
Cytochrome P450 (CYP450) gene testing is currently not recommended to guide treatment with selective serotonin reuptake inhibitor (SSRI) drugs for patients with depression, concludes an expert panel report

Antidepressants and suicidality - The debate continues

Wednesday, 5 December 2007 8:25 A GMT+01
To the Editor: Dr. Gibbons et al. pointed to recent trends in SSRI prescriptions and the rate of suicide in young people to suggest that the FDA warnings have contributed to the increase in the number of youth suicides from 2003 to 2004.

Abstract: A naturalistic long-term comparison study of SSRIs in the treatment of panic disorder.

Wednesday, 5 December 2007 8:09 A GMT+01
Selective serotonin reuptake inhibitors (SSRIs) are currently considered as the first drug of choice in the treatment of panic disorder (PD). The aim of this long-term, naturalistic comparison study was to compare 4 SSRIs

Gradual, 10% dose reductions dramatically reduce antidepressant discontinuation symptoms

Wednesday, 21 November 2007 8:06 A GMT+01
Ten percent weekly reductions in dose over 10 weeks can diminish discontinuation effects associated with many antidepressants of the selective serotonin reuptake inhibitor (SSRI) class.

Hyponatremia: A potentially serious side effect of antidepressant treatment in the elderly

Wednesday, 14 November 2007 8:51 A GMT+01
The wide margin of safety associated with the use of the SSRIs and SNRIs are a major reason these drugs have been so widely adopted.

Abstract: SSRI and Substance P antagonist enhancement of natural killercell innate immunity in HIV/AIDS

Tuesday, 23 October 2007 10:28 P GMT+01
Natural killer (NK) cells play an important role in innate immunity and are involved in the host defense against human immunodeficiency virus (HIV) infection.

Should young people be given antidepressants? No

Saturday, 13 October 2007 9:36 A GMT+01
The medical profession had endorsed the use of selective serotonin reuptake inhibitors (SSRIs) well before any of the big studies in children were published.

Should young people be given antidepressants? Yes

Saturday, 13 October 2007 9:35 A GMT+01
There are genuine reasons to question their use. Firstly, much of the evidence has, quite rightly, been strongly criticised in recent years.

SSRI antidepressants and some painkillers – a dangerous combination

Tuesday, 9 October 2007 7:48 A GMT+01
Taking selective serotonin reuptake inhibitors (SSRIs) together with non-steroidal anti-inflammatory drugs (NSAIDs) can substantially increase the risk of bleeding from the stomach, according to new research

Diabetes warning over antidepressants

Tuesday, 18 September 2007 8:50 A GMT+01
Patients taking both SSRIs and tricyclic antidepressants should be closely monitored for type 2 diabetes, researchers warn.

New study confirms antidepressants led to less, not more, teen suicides

Saturday, 8 September 2007 9:29 A GMT+01
A new study by researchers at the University of South Florida and University of Illinois suggests FDA mandated warnings about suicide in teens treated with antidepressants could have the unintended consequence of placing more youth at risk.

Abstract: Where does all the Prozac® go?

Saturday, 1 September 2007 9:17 A GMT+01
Fluoxetine is a SSRI that was introduced in 1986. Certain side effects of this medication-drowsiness, dizziness, abnormal vision, diarrhea, and headache-could affect pilot performance and become a factor in an aviation accident.

A developmental perspective on the controversy surrounding the use of SSRIs to treat pediatric depression

Thursday, 30 August 2007 9:27 A GMT+01
Since the 1990s, there has been at least a 3- to 5-fold increase in the prevalence of antidepressant treatment for U.S. youths aged 2-19 years. Although children over the age of 10 were the most likely to receive prescriptions for antidepressants,

Antipressant effectiveness predicted by gene variation

Thursday, 2 August 2007 9:47 A GMT+01
A variation in a gene called GRIK4 appears to make people with depression more likely to respond to the medication citalopram (Celexa) than are people without the variation,

Are antidepressants taking the edge off love?

Saturday, 28 July 2007 8:24 A GMT+01
Sure, we know about the sexual side effects of SSRIs. But researchers now wonder if that's the only aspect of romance the drugs can influence.

Abstract+: Issues in the pharmacological treatment of Obsessive-Compulsive Disorder

Thursday, 26 July 2007 10:24 A GMT+01
Obsessive-compulsive disorder (OCD) preferentially responds to a class of antidepressants called serotonin reuptake inhibitors.[SRI] This review discusses certain issues unique to pharmacological treatment of OCD

For anxiety, look beyond status quo drugs: Augmentation most commonly involves atypicals; benzodiazepines or buspirone; and anticonvulsants.

Wednesday, 25 July 2007 9:25 A GMT+01
Selective serotonin reuptake inhibitors and serotonin norepinephrine reuptake inhibitors are first-line pharmacotherapy for most patients with generalized anxiety disorder and social anxiety disorder, but a substantial number of patients need more.

FDA safety label changes for lorazepam (Ativan®) and fluoxetine (Sarafem®)

Wednesday, 18 July 2007 8:59 A GMT+01
The U.S. Food and Drug Administration's Center for Drug Evaluation and Research (CDER) has approved safety label changes for lorazepam (Ativan®) and fluoxetine (Sarafem®).

Abstract: SSRI reduces oxidative damage from stress

Sunday, 8 July 2007 9:20 A GMT+01
Stress plays a potential role in the onset and exacerbation of depression. Chronic restraint stress in rats, and psychosocial stress in humans, is implicated in the pathophysiology of mood and anxiety disorders.

Abstract: Large drop in depression treatment for kids following black box warnings

Friday, 6 July 2007 9:11 A GMT+01
To evaluate the effect of UK and US warnings placed in response to reports of suicidal thinking in pediatric patients receiving SSRI and SNRI antidepressants on antidepressant prescribing for children and adolescents.

Both depression drugs, psychotherapy halve suicide risk within weeks

Tuesday, 3 July 2007 10:27 A GMT+01
In a study of more than 100,000 patients treated for depression, suicide attempts declined during the first month of treatment-whether that treatment consisted of medication,psychotherapy, or both.

Abstract: Relationship between antidepressants and suicide attempts

Tuesday, 3 July 2007 10:01 A GMT+01
In late 2006, a U.S. Food and Drug Administration advisory committee recommended that the 2004 black box warning regarding suicidality in pediatric patients receiving antidepressants be extended to include young adults.

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