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Latest tagged entries for 'SEROTONIN'



Serotonin gene alters SSRI effect on some symptoms, not others

Thursday, 1 February 2007 7:43 A GMT+01
Variation in the serotonin transporter (SERTPR) gene influences the effect of selective serotonin reuptake inhibitors (SSRIs) on some clusters of depressive symptoms, but not others, researchers report.

Abstract: Platelet serotonin levels support depression scores for women with postpartum depression.

Saturday, 27 January 2007 4:29 A GMT+01
It is very challenging to make an unbiased diagnosis of psychiatric illness. Platelets have long been proposed as easily obtainable, neurological models of serotonergic neurons.

Your best antidepressant may be a matter of taste

Thursday, 7 December 2006 6:05 A GMT+01
New research has shown that it might be possible to use taste as an indicator as to whether someone is depressed, and as a way of determining which is the most suitable drug to treat their anxiety or depression.

Abstract: Antidepressant-like effects of novel triple reuptake inhibitors, PRC025 and PRC050

Monday, 20 November 2006 6:34 A GMT+01
Eur J Pharmacol. 2006 Oct 17; [Epub ahead of print] Antidepressant-like effects of novel triple reuptake inhibitors, PRC025 and PRC050. Shaw AM, Boules M, Zhang Y, Williams K, Robinson J, Carlier PR, Richelson E.

Abstract: Elevated MAO-A inhibitor protein levels may be depression theory's 'smoking gun'

Wednesday, 8 November 2006 8:45 A GMT+01
The monoamine theory of depression proposes that monoamine levels are lowered, but there is no explanation for how monoamine loss occurs. Monoamine oxidase A is an enzyme that metabolizes monoamines such as serotonin, norepinephrine, and dopamine.

Abusive childhood may permanently lower brain serotonin spanning generations

Friday, 3 November 2006 7:39 A GMT+01
Research conducted at the University of Chicago has shown infant abuse may be perpetuated between generations by changes in the brain induced by the early experience.

Brain's emotion rheostat may be linked to depression

Tuesday, 3 October 2006 6:22 A GMT+01
Although drugs that target the brain's serotonin system are widely used to treat depression, the basic biological mechanism by which they help to alleviate symptoms is poorly understood.

Always happy mice key to new depression treatments

Wednesday, 23 August 2006 8:53 A GMT+01
A new breed of permanently 'cheerful' mouse is providing hope of a new treatment for clinical depression. TREK-1 is a gene that can affect transmission of serotonin in the brain. an important role in mood, sleep and sexuali

Abstract: TREK-1 - A new protein target for anxiety, depression research

Thursday, 17 August 2006 8:45 A GMT+01
Nat Neurosci. 2006 Aug 13; [Epub ahead of print] Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype. Heurteaux C, Lucas G, Guy N, El Yacoubi M, Thummler S, Peng XD, Noble F, Blondeau N, Widmann C, Borsotto

Mice lacking the 5-HT2A serotonin receptor are less anxious

Saturday, 29 July 2006 7:05 A GMT+01
The neural basis of anxiety first began to become clear in the 1980s, when researchers discovered that a drug used to treat anxiety stimulates receptors for a neurotransmitter called serotonin.

New genetic test to help treat depression

Wednesday, 19 July 2006 9:30 A GMT+01
Genetic test will screen for side effects of antidepressant treatment Mayo Clinic is offering a new genetic test to help physicians identify patients who are likely to have side effects from drugs commonly used to treat depression.

Magic mushrooms could help anxiety disorders and depression

Wednesday, 12 July 2006 7:44 A GMT+01
Using unusually rigorous scientific conditions and measures, Johns Hopkins researchers have shown that the active chemical in "sacred mushrooms" can induce mystical/spiritual experiences

Damaged DNA: Depression's hidden culprit?

Sunday, 2 July 2006 5:02 A GMT+01
Does a deficiency of the monoamines serotonin, norepinephrine, and dopamine cause depression? New evidence from the University of Texas Southwest Medical Center challenges this popular "chemical imbalance" theory,

Study to test amino acids levels as indicator of depression

Monday, 5 June 2006 4:10 A GMT+01
Could a test involving a simple drink help predict who is at risk for depression? That's what local doctors are trying to find out, and San Antonians can help in this important new study. Chemical changes deep inside the brain put millions of people

Abstract: Effects of different doses of venlafaxine (Effexor®) on serotonin and norepinephrine reuptake

Monday, 15 May 2006 10:23 A GMT+01
Int J Neuropsychopharmacol. 2006 May 11;:1-10 [Epub ahead of print] Effects of different doses of venlafaxine on serotonin and norepinephrine reuptake in healthy volunteers. Blier P, Saint-Andre E, Hebert C, de Montigny C, Lavoie N, Debonnel G.Depart

Abstract: Mechanisms of action of current and potential pharmacotherapies of OCD

Sunday, 23 April 2006 6:17 A GMT+01
Prog Neuropsychopharmacol Biol Psychiatry 2006 May; 30(3):362-373Mechanisms of action of current and potential pharmacotherapies of obsessive-compulsive disorder El Mansari M, Blier P. University of Ottawa Institute of Mental Health Research, Lady G

Serotonin and Anxiety/Depression: A Disconnect between the Advertisements and the Scientific Literature

Thursday, 10 November 2005 8:46 A GMT+01
Comment:  The authors make some very valid points, which is why this article is being posted in full. The "chemical imbalance" theory of mental illness is not supported by research and our knowledge of the brain mechanisms that produce disorders